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European cystic fibrosis bone mineralisation guidelines

Isabelle Sermet-Gaudelus, Maria Luisa Bianchi, Michèle Garabédian, Robert M. Aris, Alison Morton, Dana S. Hardin, Sarah L. Elkin, Juliet E. Compston, Steven P. Conway, Mireille Castane, Susan Wolfe, Charles S. Haworth

Abstract


Patients with cystic fibrosis (CF) are at risk of developing low bone mineral density (BMD) and fragility fractures. This paper presents consensus statements that summarise current knowledge of the epidemiology and pathophysiology of CF-related skeletal deficits and provides guidance on its assessment, prevention and treatment. The statements were validated using a modified Delphi methodology.

© 2011 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.

Keywords: Cystic fibrosis; Dual Energy X-ray Absorptiometry (DXA); Bone density; Fractures; Bisphosphonates; Calcium; Vitamin D; Puberty

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